Welcome!
We are the white matter interdisciplinary team.
We investigate genetic white matter disorders and their overlap with acquired myelin disorders, such as the multiple sclerosis spectrum.
Our research goals are
1. to identify new forms of adult hereditary white matter disorders and their causal genes
2. to enhance our abilities to discriminate between genetic leukoencephalopathies and acquired myelin disorders
3. to define novel diagnostic pointers and imaging biomarkers in hereditary spastic paraparesis and ataxias by investigating the presence of white matter abnormalities
We use an interdisciplinary approach that combines deep clinical phenotyping with advanced imaging techniques and next-generation sequencing analysis.